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Peptide Analogs
A synthetic pentapeptide with non-coded residues and a C-terminal amide, characterized in receptor-binding and structure-activity studies.
Reviewed by Dr. James Whitfield, PharmD · Published · Last reviewed · For research use only.
Type
Synthetic peptide (pentapeptide)
Molecular formula
C38H49N9O5
Molecular weight
711.9 g/mol
CAS number
170851-70-4
Amino acids
5
Sequence
Aib-His-D-2-Nal-D-Phe-Lys-NH2
Modification
N-terminal Aib; D-2-naphthylalanine; D-Phe; C-terminal amide.
A synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) studied for its binding to a class A G-protein-coupled receptor in receptor-pharmacology assays. Non-coded residues (Aib, D-2-naphthylalanine, D-Phe) and C-terminal amidation are structural features examined for their contribution to binding selectivity and proteolytic stability across the analog series.
Lyophilized
20°C
typically stable 24-36 months desiccated and protected from light.
Avoid freeze-thaw; aliquot; protect from light and moisture.
Reviews
Buscail E, Deraison C. (2022). Br J Pharmacol
Ishida J, et al. (2020). JCSM Rapid Communications
Sinha DK, et al. (2020). Transl Androl Urol
Clinical
Beck DE, et al. (2014). Int J Colorectal Dis
Gobburu JVS, et al. (1999). Pharm Res
Primary research
Mohammadi E, et al. (2020). J Exp Pharmacol
Semenistaya E, et al. (2015). Drug Test Anal
Greenwood-Van Meerveld B, et al. (2012). J Exp Pharmacol
Aagaard NK, et al. (2009). Growth Horm IGF Res
Venkova K, et al. (2009). J Pharmacol Exp Ther
Adeghate E, Ponery AS. (2004). Neuro Endocrinol Lett
Jiménez-Reina L, et al. (2002). Histol Histopathol
Andersen NB, et al. (2001). Growth Horm IGF Res
Lall S, et al. (2001). Biochem Biophys Res Commun
Svensson J, et al. (2000). J Endocrinol
Malmlöf K, et al. (2000). Growth Horm IGF Res
Johansen PB, et al. (1999). Growth Horm IGF Res
Ankersen M, et al. (1998). J Med Chem
Raun K, et al. (1998). Eur J Endocrinol
Research Use Only
These products are intended for research purposes only and are not for human consumption. Not FDA approved. Not intended to diagnose, treat, cure, or prevent any disease.
| Compound | Type | Molecular weight | CAS number |
|---|---|---|---|
| IpamorelinThis page | Synthetic peptide (pentapeptide) | 711.9 g/mol | 170851-70-4 |
| LUV RT | Synthetic peptide (acylated, 39 residues) | ~4,731 Da | 2381089-83-2 |
| LUV SM | Synthetic peptide (acylated, 31 residues) | ~4,114 g/mol | 910463-68-2 |
| LUV TRZ2 | Synthetic linear peptide (acylated, 39 residues) | ~4,814 g/mol | 2023788-19-2 |
| AOD-9604 | Synthetic peptide (cyclic, 16 residues) | ~1,815 g/mol | 221231-10-3 |
Comparison of laboratory reference specifications only. For research use only; not a therapeutic comparison.
Quality & methods