GH Secretagogue
A secretagogue peptide studied in preclinical research.
Type
Synthetic peptide (hexapeptide)
Molecular formula
C47H58N12O6
Molecular weight
887.04 g/mol
CAS number
140703-51-1
Amino acids
6
Sequence
His-D-2-MeTrp-Ala-Trp-D-Phe-Lys-NH2
Modification
D-2-methyltryptophan; D-Phe; C-terminal amide.
A synthetic hexapeptide that binds the GHS-R1a (ghrelin) receptor, a class A GPCR, and has also been characterized as a ligand of the scavenger receptor CD36.
Research Focus
Studied in GHS-R1a and CD36 receptor pharmacology and cardiovascular research models.
Lyophilized
-20°C
typically stable 24-36 months desiccated.
Reconstituted
2-8°C short-term
-20°C/-80°C for longer storage.
Avoid freeze-thaw; aliquot; protect from light and moisture.
Reviews
Mao Y, et al. (2014). J Geriatr Cardiol — Review of GH-independent cardiovascular actions (GHSR1a and CD36)
Clinical
Imbimbo BP, et al. (1994). Eur J Clin Pharmacol — Phase 1 growth-hormone-response study in healthy adults
Also known as: Examorelin
Research Use Only
These products are intended for research purposes only and are not for human consumption. Not FDA approved. Not intended to diagnose, treat, cure, or prevent any disease.
