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Peptide blend
Molecular formula
C12H19N3O8
Molecular weight
333.29 g/mol
Sequence
Ala-Glu-Asp
Molecular formula
C62H98N16O22
Molecular weight
1,419.5 g/mol
CAS number
137525-51-0
Sequence
GEPPPGKPADDAGLV
Molecular formula
C38H68N10O14
Molecular weight
889.0 g/mol
CAS number
885340-08-9
Sequence
Ac-LKKTETQ
Molecular formula
C16H30N4O4
Molecular weight
342.43 g/mol
CAS number
67727-97-3
Sequence
Lys-Pro-Val
This blend combines four structurally and mechanistically distinct molecules. Cartalax (Ala-Glu-Asp; AED) belongs to the class of ultrashort peptide bioregulators studied for proposed nuclear-entry and interaction with histone proteins and DNA promoter sequences, with downstream changes in structural matrix protein transcription examined in cell-culture models. BPC-157 is a 15-residue synthetic peptide whose primary literature maps to the nitric oxide (NO) system and VEGFR2-associated pathways — specifically the VEGFR2–Akt–eNOS and Src–Caveolin-1–eNOS axes — as well as growth-hormone-receptor-linked transcriptional readouts in fibroblast models. TB-500, characterized in the indexed literature as an N-terminally acetylated heptapeptide (Ac-LKKTETQ) corresponding to an actin-binding region within a larger endogenous peptide, is studied in the context of G-actin sequestration and cytoskeletal dynamics; this short sequence and the full-length precursor are not established as equivalent and findings from each are attributed separately. KPV (Lys-Pro-Val) is studied primarily through PepT1 (SLC15A1)-mediated intestinal uptake and downstream NF-κB and MAPK pathway engagement in epithelial and immune cell models. The blend has no single shared molecular target; each component is associated with distinct receptor contexts and signaling programs.
Lyophilized
20°C for long-term preservation
protect from light and moisture.
Multi-peptide formulation; individual component stabilities vary
Reviews
Sikiric P, et al. (2016). Curr Neuropharmacol
Goldstein AL, Hannappel E, Kleinman HK. (2005). Trends Mol Med
Reviews
Vasireddi N, et al. (2025). HSS J
McGuire FP, et al. (2025). Curr Rev Musculoskelet Med
Khavinson VKh, et al. (2021). Molecules
Primary research
Chang CH, et al. (2011). J Appl Physiol (1985)
Dalmasso G, et al. (2008). Gastroenterology
Khavinson VKh, et al. (2001). Bull Exp Biol Med
Hsieh MJ, et al. (2020). Sci Rep
Hsieh MJ, et al. (2017). J Mol Med (Berl)
Chang CH, et al. (2014). Molecules
Xiao B, et al. (2017). Mol Ther
Viennois E, et al. (2016). Cell Mol Gastroenterol Hepatol
Kannengiesser K, et al. (2008). Inflamm Bowel Dis
Sun J, et al. (2021). ACS Biomater Sci Eng
Ho EN, et al. (2012). J Chromatogr A
Khavinson VKh, et al. (2016). Bull Exp Biol Med
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