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Type
Tripeptide copper(II) complex
Molecular formula
C14H24CuN6O4
Molecular weight
~403.9 g/mol (free GHK ligand 340.4 g/mol)
CAS number
89030-95-5
Amino acids
3
Sequence
Gly-His-Lys + Cu(II)
Modification
Copper(II) complex of Gly-His-Lys; Cu coordinated by the N-terminal amine, backbone amide nitrogen and histidine imidazole.
The copper(II) coordination complex of the tripeptide glycyl-L-histidyl-L-lysine, functioning structurally as a high-affinity copper carrier. Research characterizes its interactions with extracellular-matrix and copper-dependent pathways.
Lyophilized
20°C, sealed and protected from light/moisture
stable months to years.
A blue/violet color indicates intact copper coordination; avoid freeze-thaw; aqueous stability is pH-dependent.
Reviews
Mortazavi SM, et al. (2024). BioImpacts
Pickart L, Margolina A. (2018). Int J Mol Sci
Reviews
Pickart L, et al. (2015). BioMed Research International
Pickart L, et al. (2012). Oxid Med Cell Longev
Gorouhi F, Maibach HI. (2009). Int J Cosmet Sci
Maquart FX, et al. (2005). Biochimie
Clinical
Lee WJ, et al. (2016). Ann Dermatol
Mulder GD, et al. (1994). Wound Repair Regen
Primary research
Mao S, et al. (2025). Front Pharmacol
Greco V, et al. (2025). Bioconjug Chem
Bian Y, et al. (2024). Redox Biology
Zhang Q, et al. (2022). Front Mol Biosci
Ma WH, et al. (2020). Life Sciences
Klontzas ME, et al. (2019). Acta Biomaterialia
Choi HR, et al. (2012). J Pept Sci
Campbell JD, et al. (2012). Genome Medicine
Hureau C, et al. (2011). Chem Eur J
Gul NY, et al. (2008). Vet Dermatol
Arul V, et al. (2007). Life Sciences
Cangul IT, et al. (2006). Vet Dermatol
Canapp SO, et al. (2003). Vet Surg
Conato C, et al. (2001). Biochim Biophys Acta
Siméon A, et al. (2000). J Invest Dermatol
Siméon A, et al. (2000). Life Sciences
Maquart FX, et al. (1993). J Clin Invest
Wegrowski Y, et al. (1992). Life Sciences
Maquart FX, et al. (1988). FEBS Letters
Lau SJ, Sarkar B. (1981). Biochem J
Pickart L, et al. (1980). Nature
Schlesinger DH, et al. (1977). Experientia
Pickart L, Thaler MM. (1973). Nature New Biology
Also known as: Copper tripeptide-1, Cu-GHK
View this compound in the Research Library →GHK-Cu arrived in protective packaging with professional labeling.
The QR code on the vial linked to the batch-specific third-party COA confirming the stated specifications. Lot traceability was accurate. Support responded promptly to a handling question. Documentation met research standards.
The copper-binding tripeptide (Gly-His-Lys) was received with secure...
The copper-binding tripeptide (Gly-His-Lys) was received with secure packaging and clear lot marking. Third-party COA was directly accessible via the vial QR code and matched the printed identification. Appropriate for research laboratory use.
GHK-Cu purity and lot verified via QR COA.
Secure packaging. Prompt dispatch. Clean documentation.
ghk-cu qr worked perfect, coa matched the lot, packaging was secure, shipped quick
got the ghk-cu in yesterday, order shipped same day, qr scan brought up...
got the ghk-cu in yesterday, order shipped same day, qr scan brought up the exact coa and the lot on the vial matched, packaging was clean and protective, support had replied same day when i asked about the batch, everything checked out for research use
GHK-Cu QR matched COA.
Lot verified. Good packaging. Fast ship.
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