Secretagogue
Type
Synthetic peptide (hexapeptide)
Molecular formula
C45H55N9O6
Molecular weight
817.97 g/mol
CAS number
158861-67-7
Amino acids
6
Sequence
D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
Modification
N-terminal D-Ala; D-2-naphthylalanine; D-Phe; C-terminal amide.
A synthetic hexapeptide that binds the GHS-R1a (ghrelin) receptor, a class A GPCR on pituitary somatotrophs.
Research Focus
Studied in GHS-R1a receptor pharmacology and growth-hormone-secretion research.
Lyophilized
-20°C
typically stable 24-36 months desiccated.
Reconstituted
2-8°C short-term
-20°C/-80°C for longer storage.
Avoid freeze-thaw; aliquot; protect from light and moisture.
Reviews
Adis Editorial. (2004). Drugs in R&D — Profile of pralmorelin as a synthetic GH secretagogue
Clinical
Kimura T, et al. (2010). Endocrine Journal — Clinical case series of ACTH responses to GHRP-2 versus CRH and insulin hypoglycemia
Gondo RG, et al. (2001). J Clin Endocrinol Metab — GH response to GHRP-2 in patients with GHRH-receptor mutations versus controls
Also known as: Pralmorelin
Research Use Only
These products are intended for research purposes only and are not for human consumption. Not FDA approved. Not intended to diagnose, treat, cure, or prevent any disease.
