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For Research Purposes Only
Out of StockMolecular Profile
Molecular Profile
Type
Synthetic peptide (hexapeptide)
Molecular formula
C46H56N12O6
Molecular weight
873.0 g/mol
CAS number
87616-84-0
Amino acids
6
Sequence
His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Modification
D-Trp and D-Phe; C-terminal amide.
Mechanism & Target Class
Mechanism & Target Class
A synthetic hexapeptide, His-D-Trp-Ala-Trp-D-Phe-Lys-NH2, bearing a C-terminal amide and two D-amino-acid substitutions (D-Trp at position 2, D-Phe at position 5) that confer protease resistance to the L-amino-acid backbone. In structural-pharmacology studies it serves as a tool ligand for a class A GPCR, where the compact six-residue scaffold defines a distinct binding pose within the receptor's orthosteric pocket.
Storage & Handling
Storage & Handling
Lyophilized
20°C
typically stable 24-36 months desiccated.
Avoid freeze-thaw; aliquot; protect from light and moisture.
References
References
Reviews
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Berlanga-Acosta J, et al. (2016). Integr Mol Med
Clinical
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Micic D, et al. (1998). J Clin Endocrinol Metab
- 9
Veldhuis JD, Bowers CY (2009). Am J Physiol Endocrinol Metab
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Hernández-Bernal F, et al. (2024). Front Neurol
Primary research
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Frago LM, et al. (2002). Endocrinology
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Frago LM, et al. (2005). J Neuroendocrinol
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Berlanga J, et al. (2007). Clin Sci (Lond)
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Qiu WC, et al. (2008). World J Gastroenterol
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García Del Barco D, et al. (2011). Neurotoxicol Res
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García del Barco D, et al. (2011). Restor Neurol Neurosci
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García Del Barco-Herrera D, et al. (2013). Restor Neurol Neurosci
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Yahashi S, et al. (2012). Peptides
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Subirós N, et al. (2016). Neurol Res
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Mendoza Marí Y, et al. (2016). Plast Surg Int
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Subirós N, et al. (2016). Neurol Res
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Fernández-Mayola M, et al. (2018). Int Wound J
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Berlanga-Acosta J, et al. (2024). Front Pharmacol
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Wang L, et al. (2026). Pharmaceuticals (Basel)
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Wang L, et al. (2026). Int Immunopharmacol
Primary Database
Primary Database
Research Use Only. All products sold by Luvaminos are intended solely for in vitro research and laboratory use by qualified professionals. They are not approved by the FDA and are not intended for human or animal consumption, therapeutic use, or diagnostic purposes. By purchasing, you confirm you are a licensed researcher or institution and accept full responsibility for compliance with all applicable laws and regulations.
