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For Research Purposes Only
Out of StockThymalin
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$49.99Size
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Molecular Profile
Molecular Profile
Type
Thymic peptide preparation (polypeptide complex)
Mechanism & Target Class
Mechanism & Target Class
A complex of low-molecular-weight polypeptides extracted from thymus tissue, studied in the bioregulator literature as a thymic immunomodulatory preparation. Research characterizes the preparation as acting on lymphoid and myeloid cell populations, with reported effects on thymocyte blastogenesis, differentiation, proliferation, and apoptosis. Mechanistic work has examined intracellular signal transduction, including signaling along the sphingomyelin pathway in thymocytes (Khavinson et al., 2002), and has framed the preparation's activity within a broader peptide-bioregulator model in which short thymic peptides modulate tissue-specific cell differentiation across age. Investigators have associated defining short-peptide dipeptide motifs (reported in the preparation context as KE and EW dipeptides) with gene-expression and protein-synthesis readouts in research models (Linkova et al., 2023). Because Thymalin is a polypeptide complex rather than a single defined molecule, no single high-affinity receptor, molecular formula, or molecular weight is established for the preparation across the literature.
Storage & Handling
Storage & Handling
Lyophilized
Store cool and dry as a lyophilized powder
protect from heat, light, and moisture.
Polypeptide complex rather than a single defined peptide; handle as a peptide preparation, aliquot to minimize freeze–thaw exposure, and protect from heat and light.
References
References
Reviews
- 1
Khavinson VKh, Morozov VG. (2003). Neuro Endocrinology Letters
- 2
Khavinson VKh, Morozov VG. (2002). Advances in Gerontology (Uspekhi Gerontologii)
Reviews
- 3
Khavinson VKh. (2002). Neuro Endocrinology Letters
- 4
Khavinson VK. (2001). Bulletin of Experimental Biology and Medicine
- 5
Morozov VG, Khavinson VK. (1997). International Journal of Immunopharmacology
Clinical
- 6
Kuznik BI, Shapovalov KG, Smolyakov YN, Lukyanov SA, Tereshkov PP, Kazantseva LS. (2022). Advances in Gerontology (Uspekhi Gerontologii)
- 7
Khavinson VK, Kuznik BI, Trofimova SV, Volchkov VA, Rukavishnikova SA, Titova ON. (2021). Stem Cell Reviews and Reports
- 8
Litvinenko GI, Shurlygina AV, Dergacheva TI, Mel'nikova EV, Trufakin VA. (2015). Bulletin of Experimental Biology and Medicine
- 9
Tsybikov MN, Likhanov ID, Borshchevskii VS, Kuznik BI, Tsepelev VL, Maslo EYu. (2012). Khirurgiia (Surgery)
Primary research
- 10
Linkova N, Khavinson V, Diatlova A, Petukhov M, Vladimirova E, Sukhareva M. (2023). International Journal of Molecular Sciences
- 11
Avolio F, Martinotti S, Khavinson VK, Esposito JE, Giambuzzi G, Marino A, et al. (2022). International Journal of Molecular Sciences
- 12
Khavinson VK, Linkova NS, Kvetnoy IM, Polyakova VO, Drobintseva AO, Kvetnaia TV. (2020). Bulletin of Experimental Biology and Medicine
- 13
Zhukova GV, Schikhlyarova AI, Barteneva TA, Shevchenko AN, Zakharyuta FM. (2018). Bulletin of Experimental Biology and Medicine
- 14
Ryzhak AP, Chalisova NI, Lin'kova NS, Khalimov RI, Ryzhak GA, Zhekalov AN. (2015). Advances in Gerontology (Uspekhi Gerontologii)
- 15
Kuznetsova TA, Besednova NN, Zaporozhets TS, Smolina TP, Kazha AK, Ivanushko LA. (2013). Antibiotics and Chemotherapy (Antibiotiki i Khimioterapiia)
- 16
Sevostianova NN, Linkova NS, Polyakova VO, Chervyakova NA, Kostylev AV, Durnova AO. (2013). Bulletin of Experimental Biology and Medicine
- 17
Lin'kova NS, Polyakova VO, Trofimov AV, Kvetnoy IM, Khavinson VKh. (2011). Bulletin of Experimental Biology and Medicine
- 18
Labunets IF, Rodnichenko AE, Magdich LV, Butenko GM. (2011). Advances in Gerontology (Uspekhi Gerontologii)
- 19
Labunets' IF. (2007). Advances in Gerontology (Uspekhi Gerontologii)
- 20
Khlystova ZS, Kalinina II, Shmeleva SP. (2003). Bulletin of Experimental Biology and Medicine
- 21
Khavinson VKh, Malinin VV, Chalisova NI, Grigor'ev EI. (2002). Advances in Gerontology (Uspekhi Gerontologii)
- 22
Khavinson VKh, Rybakina EG, Malinin VV, Pivanovich IY, Shanin SN, Korneva EA. (2002). Bulletin of Experimental Biology and Medicine
- 23
Khavinson VKh, Kozhemiakin AL, Volgarev AP, Platonov VG. (1993). Journal of Microbiology, Epidemiology and Immunobiology
Also known as: Timalin, Thymalin (thymic polypeptide preparation)
View this compound in the Research Library →Research Use Only. All products sold by Luvaminos are intended solely for in vitro research and laboratory use by qualified professionals. They are not approved by the FDA and are not intended for human or animal consumption, therapeutic use, or diagnostic purposes. By purchasing, you confirm you are a licensed researcher or institution and accept full responsibility for compliance with all applicable laws and regulations.
