Cellular
A tetrapeptide studied in preclinical cellular research.
Type
Synthetic peptide (tetrapeptide)
Molecular formula
C14H22N4O9
Molecular weight
390.35 g/mol
CAS number
307297-39-8
Amino acids
4
Sequence
Ala-Glu-Asp-Gly (AEDG)
Modification
Free termini.
A short synthetic tetrapeptide reported to interact with DNA and with regulation of the telomerase catalytic subunit (hTERT) at the gene-expression level; it has no assigned membrane receptor.
Research Focus
Studied in telomere-biology, cellular-senescence and gerontology research models.
Lyophilized
-20°C long term
0-4°C short term.
Reconstituted
2-8°C
use within days to weeks; avoid freeze-thaw.
Hygroscopic short peptide; protect from light and moisture.
Reviews
Khavinson VKh, et al. (2009). Bull Exp Biol Med — Peptide-bioregulator and aging review
Clinical
Korkushko OV, et al. (2004). Bull Exp Biol Med — Pineal melatonin-rhythm study in an elderly cohort
Primary research
Anisimov VN, et al. (2003). Biogerontology — Aging-biomarker and lifespan study (SHR mice)
Khavinson VKh, et al. (2003). Bull Exp Biol Med — Telomerase-activity study in human somatic cells
Also known as: Epitalon, AEDG peptide
Research Use Only
These products are intended for research purposes only and are not for human consumption. Not FDA approved. Not intended to diagnose, treat, cure, or prevent any disease.
