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For Research Purposes Only
Out of StockVesugen
Third-Party TestedPurity Standards
Total
$49.99Size
Quantity
1
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Molecular Profile
Molecular Profile
Type
Synthetic linear tripeptide
Molecular formula
C15H26N4O8
Molecular weight
390.39 g/mol
Amino acids
3
Sequence
Lys-Glu-Asp (KED); H-Lys-Glu-Asp-OH
Modification
Free N- and C-termini (no modifications).
Mechanism & Target Class
Mechanism & Target Class
Vesugen belongs to the class of ultrashort peptide bioregulators (2–4 residues) studied by the Khavinson group. The proposed mechanism centers on direct interaction of the small peptide with DNA: molecular-docking work places KED in the minor groove of double-stranded DNA, where it is hypothesized to associate with gene-promoter regions and influence transcription in a tissue-associated manner. Docking studies have examined KED binding to promoter regions including the MKI67 gene (encoding the proliferation marker Ki-67). Because of its small size and charged lysine residue, transport modeling has explored candidate uptake via LAT-family amino-acid transporters and the PEPT1 peptide transporter. This DNA-interaction model is the originating group's hypothesis and is not independently established consensus pharmacology.
Storage & Handling
Storage & Handling
Lyophilized
Store desiccated at -20°C
protect from light and moisture.
Small linear peptide susceptible to degradation in aqueous solution; handle under standard sterile peptide-laboratory practice.
References
References
Reviews
- 1
Khavinson VK, Linkova NS, Rudskoy AI, Petukhov MG (2023). Biomolecules
- 2
Ilina A, Khavinson V, Linkova N, Petukhov M (2022). International Journal of Molecular Sciences
Reviews
- 3
Khavinson V, Linkova N, Kozhevnikova E, Dyatlova A, Petukhov M (2022). International Journal of Molecular Sciences
- 4
Khavinson VK, Lin'kova NS, Umnov RS (2021). Bulletin of Experimental Biology and Medicine
- 5
Khavinson VK, Popovich IG, Linkova NS, Mironova ES, Ilina AR (2021). Molecules
- 6
Anisimov VN, Khavinson VKh (2010). Biogerontology
- 7
Khavinson V, Linkova N, Diatlova A, Trofimova S (2020). Stem Cell Reviews and Reports
- 8
Khavinson V, Linkova N, Dyatlova A, Kantemirova R, Kozlov K (2022). Cells
Clinical
- 9
Kitachev KV, Sazonov AB, Kozlov KL, Petrov KIu, Sliusarev AS, Khavinson VKh (2014). Advances in Gerontology
Primary research
- 10
Khavinson V, Ilina A, Kraskovskaya N, Linkova N, Kolchina N, Mironova E, Erofeev A, Petukhov M (2025). Pharmaceuticals (Basel)
- 11
Khavinson V, Ilina A, Kraskovskaya N, Linkova N, Kolchina N, Mironova E, Erofeev A, Petukhov M (2021). Pharmaceuticals (Basel)
- 12
Sinjari B, Diomede F, Khavinson V, Mironova E, Linkova N, Trofimova S, Trubiani O, Caputi S (2020). Stem Cell Reviews and Reports
- 13
Kraskovskaya NA, Kukanova EO, Lin'kova NS, Popugaeva EA, Khavinson VKh (2017). Bulletin of Experimental Biology and Medicine
- 14
Kozlov KL, Bolotov II, Linkova NS, Drobintseva AO, Khavinson VK, Dyakonov MM, Kozina LS (2016). Advances in Gerontology
- 15
Khavinson VKh, Lin'kova NS, Tarnovskaya SI (2016). Bulletin of Experimental Biology and Medicine
- 16
Khavinson VKh, Tarnovskaia SI, Lin'kova NS, Guton EO, Elashkina EV (2014). Advances in Gerontology
- 17
Khavinson VKh, Tarnovskaya SI, Linkova NS, Pronyaeva VE, Shataeva LK, Yakutseni PP (2013). Bulletin of Experimental Biology and Medicine
- 18
Caputi S, Trubiani O, Sinjari B, Trofimova S, Diomede F, Linkova N, Diatlova A, Khavinson V (2019). International Journal of Immunopathology and Pharmacology
- 19
Ashapkin V, Khavinson V, Shilovsky G, Linkova N, Vanuyshin B (2020). Molecular Biology Reports
- 20
Kolchina N, Khavinson V, Linkova N, Yakimov A, Baitin D, Afanasyeva A, Petukhov M (2019). Nucleic Acids Research
- 21
Sakhenberg E, Linkova N, Kraskovskaya N, Krieger D, Polyakova V, Medvedev D, Krasichkov A, Khotin M, Ryzhak G (2025). Current Issues in Molecular Biology
Primary Database
Primary Database
Also known as: KED, Lys-Glu-Asp
View this compound in the Research Library →Research Use Only. All products sold by Luvaminos are intended solely for in vitro research and laboratory use by qualified professionals. They are not approved by the FDA and are not intended for human or animal consumption, therapeutic use, or diagnostic purposes. By purchasing, you confirm you are a licensed researcher or institution and accept full responsibility for compliance with all applicable laws and regulations.
