Luvaminos

Adamax

A synthetic Semax analogue: the N-acetylated Semax sequence extended by Ala-Gly to nine residues, ending in a free carboxylic acid (984.1 g/mol).

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Quick answers

What is Adamax?

Adamax is a synthetic Semax analogue: the N-acetylated Semax sequence extended by Ala-Gly to nine residues, ending in a free carboxylic acid (984.1 g/mol). It is a synthetic peptide (Semax analogue, 9 residues) with a molecular weight of 984.10 g/mol and the formula C44H61N11O13S.

How much published research cites Adamax?

The Luvaminos Adamax record cites 22 published references, dated 2001 to 2025. Each is listed on this page with a link to its source.

Does Luvaminos test Adamax, and where is the certificate?

Yes. Every Adamax lot Luvaminos sells is tested by Freedom Diagnostics Testing, PLLC, an independent laboratory. The current 10 mg lot, ADA-10-001, measured 99.81% purity by HPLC and a net content of 11.29 mg, tested October 15, 2026. Its certificate is published at luvaminos.com/coa/ADA-10-001.

What modifications does Adamax carry?

Adamax: N-terminal acetylation; an Ala-Gly extension after the Semax sequence; a free C-terminal carboxylic acid.

How is Adamax powder stored?

Sealed Adamax powder: Store refrigerated or at −20 °C, protected from light; use desiccant as needed. Avoid repeated freeze-thaw cycles; protect from light and microbial contamination.

How is Adamax different from Semax?

Adamax and Semax are different compounds: Adamax has 9 amino acids, a molecular weight of 984.10 g/mol and formula C44H61N11O13S; Semax has 7 amino acids, a molecular weight of 813.93 g/mol and formula C37H51N9O10S. Adamax: N-terminal acetylation. Semax: C-terminal Pro-Gly-Pro tripeptide extension of the ACTH(4-7) core.

How is Adamax different from N-Acetyl Semax?

Adamax and N-Acetyl Semax are different compounds: Adamax has 9 amino acids, a molecular weight of 984.10 g/mol and formula C44H61N11O13S; N-Acetyl Semax has 7 amino acids, a molecular weight of 855.0 g/mol and formula C39H54N10O10S. Adamax: N-terminal acetylation. N-Acetyl Semax: N-terminal acetylation and C-terminal amidation of the parent Semax heptapeptide (CAS 80714-61-0).

Molecular Profile

Type
Synthetic peptide (Semax analogue, 9 residues)
Molecular formula
C44H61N11O13S
Molecular weight
984.10 g/mol
Amino acids
9
Sequence
Ac-Met-Glu-His-Phe-Pro-Gly-Pro-Ala-Gly-OH
Modification
N-terminal acetylation; an Ala-Gly extension after the Semax sequence; a free C-terminal carboxylic acid.

Mechanism & Target Class

A synthetic peptide built on the Semax sequence (Met-Glu-His-Phe-Pro-Gly-Pro), itself an analogue of the ACTH(4–10) fragment. The N-terminus is acetylated and the chain is extended by Ala-Gly, ending in a free carboxylic acid. N-terminal acetylation and C-terminal extension are modifications studied in peptide analogues for their effect on resistance to enzymatic degradation. Its molecular weight is 984.1 g/mol (monoisotopic mass 983.42 Da).

Storage & Handling

Lyophilized
Store refrigerated or at −20 °C, protected from light; use desiccant as needed.
Handling
Avoid repeated freeze-thaw cycles; protect from light and microbial contamination.

References (22)

  1. Reviews

    1

    Markov DD, Dolotov OV, Grivennikov IA (2023). Int. J. Mol. Sci.

    DOI: 10.3390/ijms24076664

  2. Primary research

    2

    Li B, et al. (2010). FEBS Lett

    DOI: 10.1016/j.febslet.2010.06.025PubMed 20600002

  3. 3

    Dolotov OV, et al. (2006). Brain Res

    DOI: 10.1016/j.brainres.2006.07.108PubMed 16996037

  4. 4

    Radchenko AI, Sobolevsky OI, et al. (2025). Acta Naturae

    DOI: 10.32607/actanaturae.27808

  5. 5

    Sciacca MFM, Naletova I, Giuffrida ML, Attanasio F (2022). ACS Chem. Neurosci.

    DOI: 10.1021/acschemneuro.1c00707PubMed 35080861

  6. 6

    Sudarkina OY, Remizova JA, et al. (2021). Int. J. Mol. Sci.

    DOI: 10.3390/ijms22126179

  7. 7

    Dolotov OV, Karpenko EA, Seredenina TS, et al. (2006). J. Neurochem.

    DOI: 10.1111/j.1471-4159.2006.03658.x

  8. 8

    Medvedeva EM, Dergunova LV, Filippenkov IB, et al. (2014). BMC Genomics

    DOI: 10.1186/1471-2164-15-228PubMed 24666732

  9. 9

    Dolotov OV, Karpenko EA, Inozemtseva LS, et al. (2006). Brain Res.

    DOI: 10.1016/j.brainres.2006.07.108PubMed 16996037

  10. 10

    Shadrina MI, Dolotov OV, Grivennikov IA, et al. (2001). Neurosci. Lett.

    DOI: 10.1016/s0304-3940(01)01994-2PubMed 11457573

  11. 11

    Agapova TY, Agniullin YV, Shadrina MI, et al. (2007). Neurosci. Lett.

    DOI: 10.1016/j.neulet.2007.02.042PubMed 17353092

  12. 12

    Shadrina M, Kolomin T, Agapova T, et al. (2009). J. Mol. Neurosci.

    DOI: 10.1007/s12031-009-9270-zPubMed 19662538

  13. 13

    Storozhevykh TP, Tukhbatova GR, Senilova YE, et al. (2007). Bull. Exp. Biol. Med.

    DOI: 10.1007/s10517-007-0192-xPubMed 18239779

  14. 14

    Grivennikov IA, Dolotov OV, Zolotarev YA, et al. (2008). Restor. Neurol. Neurosci.

    DOI: 10.3233/rnn-2008-00419PubMed 18431004

  15. 15

    Eremin KO, Kudrin VS, Saransaari P, et al. (2005). Neurochem. Res.

    DOI: 10.1007/s11064-005-8826-8PubMed 16362768

  16. 16

    Bashkatova VG, Koshelev VB, Fadyukova OE, et al. (2001). Brain Res.

    DOI: 10.1016/s0006-8993(00)03324-2PubMed 11245825

  17. 17

    Dmitrieva VG, Kolomin TA, Shadrina MI, et al. (2009). Cell Mol. Neurobiol.

    DOI: 10.1007/s10571-009-9432-0PubMed 19633950

  18. 18

    Medvedeva EV, Dmitrieva VG, Limborska SA, et al. (2017). Mol. Genet. Genomics

    DOI: 10.1007/s00438-017-1297-1PubMed 28255762

  19. 19

    Filippenkov IB, Stavchansky VV, Denisova AE, et al. (2020). Genes

    DOI: 10.3390/genes11060681PubMed 32580520

  20. 20

    Dergunova LV, Filippenkov IB, Stavchansky VV, et al. (2021). Mol. Biol.

    DOI: 10.1134/s0026893321010040PubMed 34097675

  21. 21

    Stavchansky VV, Yuzhakov VV, Sevan'kaeva LE, et al. (2024). Curr. Issues Mol. Biol.

    DOI: 10.3390/cimb46030133PubMed 38534749

  22. 22

    Filippenkov IB, Shpetko YY, Stavchansky VV, et al. (2024). Biomedicines

    DOI: 10.3390/biomedicines12122830PubMed 39767736

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About Adamax

What is Adamax?

Adamax is a synthetic Semax analogue: the N-acetylated Semax sequence extended by Ala-Gly to nine residues, ending in a free carboxylic acid (984.1 g/mol).

What are the molecular formula and molecular weight of Adamax?

Adamax: molecular formula C44H61N11O13S and molecular weight 984.10 g/mol.

What is the sequence of Adamax?

Ac-Met-Glu-His-Phe-Pro-Gly-Pro-Ala-Gly-OH.

How is Adamax powder stored?

Store refrigerated or at −20 °C, protected from light; use desiccant as needed.