AMY (CG) / LUV RT

A research peptide blend of two lipidated, acylated synthetic peptides.

Molecular Profile

Type
Peptide blend

Components

AMY (CG)

Molecular formula
C194H312N54O59S2
Molecular weight
~4,409 g/mol
CAS number
1415456-99-3

LUV RT

Molecular formula
C221H342N46O68
Molecular weight
~4,731 g/mol
CAS number
2381089-83-2

Mechanism & Target Class

A blend of two lipidated, modified synthetic peptides. In each component, fatty-acid conjugation — a C20 diacid via a Glu–Lys spacer for AMY (CG) and a C19 diacid via a γ-Glu linker for LUV RT — confers reversible albumin binding and extended plasma half-life. Non-coded residue substitutions in both peptides confer resistance to circulating proteases, and each engages class B G protein–coupled receptors as characterized in cryo-EM structural studies.

Storage & Handling

Lyophilized
-20°C or below; lyophilized powder typically stable up to 24 months in sealed, desiccated vials.
Handling
AMY (CG): high fibrillation propensity at neutral pH; avoid freeze-thaw cycles. LUV RT: aliquot to minimize freeze-thaw; protect from light and moisture.

References (22)

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