Cartalax
A synthetic tripeptide (Ala-Glu-Asp) studied in cell-culture models of connective-tissue and cellular gene-expression bioregulation.
Quick answers
What is Cartalax?
Cartalax is a synthetic tripeptide (Ala-Glu-Asp) studied in cell-culture models of connective-tissue and cellular gene-expression bioregulation. It is a synthetic linear tripeptide (short peptide bioregulator) of 3 amino acids with a molecular weight of 333.29 g/mol and the formula C12H19N3O8.
How much published research cites Cartalax?
The Luvaminos Cartalax record cites 21 published references, dated 2010 to 2023. Each is listed on this page with a link to its source.
Does Luvaminos test Cartalax, and where is the certificate?
Luvaminos does not currently stock Cartalax. Every peptide lot Luvaminos sells is tested by Freedom Diagnostics Testing, PLLC, an independent laboratory, and its certificate is published at luvaminos.com/coa under the lot number printed on the vial.
How is Cartalax powder stored?
Sealed Cartalax powder: Store sealed and protected from light, heat, and moisture; refrigerated (≤6 °C) or frozen for long-term storage per supplier documentation. Stable as a lyophilized solid under appropriate conditions; compound-specific long-term stability data are limited in the primary literature.
Molecular Profile
- Type
- Synthetic linear tripeptide (short peptide bioregulator)
- Molecular formula
- C12H19N3O8
- Molecular weight
- 333.29 g/mol
- Amino acids
- 3
- Sequence
- Ala-Glu-Asp (H-Ala-Glu-Asp-OH; AED; T-31)
- Modification
- None (unmodified free N- and C-termini)
Mechanism & Target Class
Cartalax (AED) is an ultrashort peptide of the Khavinson-class short peptide bioregulators. Its two acidic residues (glutamic and aspartic acid) confer a net negative charge in neutral (pH 7.4) aqueous conditions. The proposed mechanism is not classical receptor agonism but is described as epigenetic: class studies describe these short peptides as penetrating the cell nucleus and interacting with histone proteins and single- and double-stranded DNA — including sequence-recognition contacts in gene-promoter regions — to modulate transcription. In cell-culture experiments AED is examined for its relationship to the expression of senescence- and proliferation-associated markers including sirtuin-1, sirtuin-6, collagen I, p53, p16, p21, Ki-67, IGF1, FOXO1, TERT, and NFκB. The peptide sequence has been described as homologous to a fragment of the type XI collagen alpha-1 chain, a proposed structural basis for its connective-tissue research framing.
Storage & Handling
- Lyophilized
- Store sealed and protected from light, heat, and moisture; refrigerated (≤6 °C) or frozen for long-term storage per supplier documentation.
- Handling
- Stable as a lyophilized solid under appropriate conditions; compound-specific long-term stability data are limited in the primary literature.
Primary Database
References (21)
Reviews
1Linkova N, Khavinson V, Diatlova A, Myakisheva S, Ryzhak G (2023). International Journal of Molecular Sciences
- 2
Khavinson VK, Popovich IG, Linkova NS, Mironova ES, Ilina AR (2021). Molecules
- 3
Ashapkin VV, Linkova NS, Khavinson VKh, Vanyushin BF (2015). Biochemistry (Moscow)
- 4
Anisimov VN, Khavinson VKh (2010). Biogerontology
- 5
Khavinson VKh (2014). Advances in Gerontology (Uspekhi Gerontologii)
- 6
Ilina A, Khavinson V, Linkova N, Petukhov M (2022). International Journal of Molecular Sciences
- 7
Khavinson V, Linkova N, Dyatlova A, Kantemirova R, Kozlov K (2022). Cells
- 8
Khavinson VK, Linkova NS, Diatlova AS, Gutop EO, Orlova OA (2020). Advances in Gerontology (Uspekhi Gerontologii)
Primary research
9Ashapkin V, Khavinson V, Shilovsky G, Linkova N, Vanyushin B (2020). Molecular Biology Reports
- 10
Fridman NV, Linkova NS, Kozhevnikova EO, Gutop EO, Khavinson VKh (2020). Bulletin of Experimental Biology and Medicine
- 11
Kolchina N, Khavinson V, Linkova N, Yakimov A, Baitin D, Afanasyeva A, Petukhov M (2019). Nucleic Acids Research
- 12
Lin'kova NS, Drobintseva AO, Orlova OA, Kuznetsova EP, Polyakova VO, Kvetnoy IM, Khavinson VKh (2016). Bulletin of Experimental Biology and Medicine
- 13
Khavinson VKh, Lin'kova NS, Polyakova VO, Durnova AO, Nichik TE, Kvetnoi IM (2014). Bulletin of Experimental Biology and Medicine
- 14
Khavinson VKh, Tarnovskaia SI, Lin'kova NS, Poliakova VO, Durnova AO, Nichik TE, Kvetnoĭ IM, D'iakonov MM, Iakutseni PP (2014). Advances in Gerontology (Uspekhi Gerontologii)
- 15
Khavinson VKh, Lin'kova NS, Tarnovskaya SI (2016). Bulletin of Experimental Biology and Medicine
- 16
Khavinson VKh, Tarnovskaya SI, Linkova NS, et al. (2013). Bulletin of Experimental Biology and Medicine
- 17
Sinjari B, Diomede F, Khavinson V, Mironova E, Linkova N, Trofimova S, Trubiani O, Caputi S (2020). Stem Cell Reviews and Reports
- 18
Caputi S, Trubiani O, Sinjari B, Trofimova S, Diomede F, Linkova N, Diatlova A, Khavinson V (2019). International Journal of Immunopathology and Pharmacology
- 19
Khavinson V, Diomede F, Mironova E, Linkova N, Trofimova S, Trubiani O, Caputi S, Sinjari B (2020). Molecules
- 20
Khavinson V, Linkova N, Rudskoy AI, Petukhov MG (2023). Biomolecules
- 21
Myakisheva SN, Linkova NS, Diatlova AS, Polyakova VO, Ryzhak GA (2023). Advances in Gerontology (Uspekhi Gerontologii)
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