Luvaminos

KPV

A tripeptide fragment investigated in preclinical cellular research.

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Quick answers

What is KPV?

KPV is a tripeptide fragment investigated in preclinical cellular research. It is a synthetic peptide (tripeptide) of 3 amino acids with a molecular weight of 342.43 g/mol and the formula C16H30N4O4.

How much published research cites KPV?

The Luvaminos KPV record cites 21 published references, dated 2000 to 2025. Each is listed on this page with a link to its source.

Does Luvaminos test KPV, and where is the certificate?

Yes. Every KPV lot Luvaminos sells is tested by Freedom Diagnostics Testing, PLLC, an independent laboratory. The current 10 mg lot, KPV-10-002, measured 99.61% purity by HPLC and a net content of 10.61 mg, tested October 21, 2026. Its certificate is published at luvaminos.com/coa/KPV-10-002.

What modifications does KPV carry?

KPV: Free termini; C-terminal tripeptide of alpha-MSH (residues 11-13).

How is KPV powder stored?

Sealed KPV powder: -20°C; protect from light and moisture; ~24 months. Protect from moisture.

How is KPV different from BPC-157 + TB-500 + GHK-Cu + KPV?

KPV is a single compound; BPC-157 + TB-500 + GHK-Cu + KPV is a blend of GHK-Cu, KPV, BPC-157 and TB-500, with KPV as one of its 4 components. KPV has 3 amino acids and a molecular weight of 342.43 g/mol.

Molecular Profile

Type
Synthetic peptide (tripeptide)
Molecular formula
C16H30N4O4
Molecular weight
342.43 g/mol
CAS number
67727-97-3
Amino acids
3
Sequence
Lys-Pro-Val (KPV)
Modification
Free termini; C-terminal tripeptide of alpha-MSH (residues 11-13).

Mechanism & Target Class

The C-terminal tripeptide (Lys-Pro-Val) of alpha-MSH. It is studied in cellular research in the context of the PepT1 (SLC15A1) peptide transporter and NF-kB / MAPK signaling.

Storage & Handling

Lyophilized
-20°C; protect from light and moisture; ~24 months.
Handling
Small soluble tripeptide; protect from moisture.

Primary Database

PubChem CID 125672 ↗

References (21)

  1. Reviews

    1

    Gravina AG, et al. (2023). Cells

    DOI: 10.3390/cells12141889

  2. 2

    Brzoska T, et al. (2010). Adv Exp Med Biol

    PubMed 21222263

  3. 3

    Brzoska T, et al. (2008). Endocr Rev

    DOI: 10.1210/er.2007-0027PubMed 18612139

  4. 4

    Luger TA, Brzoska T. (2007). Ann Rheum Dis

    DOI: 10.1136/ard.2007.079780PubMed 17934097

  5. 5

    Luger TA, et al. (2003). Ann N Y Acad Sci

    DOI: 10.1111/j.1749-6632.2003.tb03172.xPubMed 12851308

  6. 6

    Dinparastisaleh R, Mirsaeidi M. (2021). Pharmaceuticals (Basel)

    DOI: 10.3390/ph14010045PubMed 33430064

  7. 7

    Adnan SB, et al. (2025). Int J Med Sci

    DOI: 10.7150/ijms.118118PubMed 41209547

  8. Primary research

    8

    Sung J, et al. (2025). Tissue Cell

    PubMed 40073467

  9. 9

    Preclinical delivery study (2024). Front Pharmacol

    DOI: 10.3389/fphar.2024.1442876

  10. 10

    Preclinical hydrogel study (2021). PubMed

    PubMed 34547895

  11. 11

    Pawar K, et al. (2017). J Pharm Sci

    DOI: 10.1016/j.xphs.2017.03.017PubMed 28343991

  12. 12

    Xiao B, et al. (2017). Mol Ther

    DOI: 10.1016/j.ymthe.2016.11.020PubMed 28143741

  13. 13

    Viennois E, et al. (2016). Cell Mol Gastroenterol Hepatol

    DOI: 10.1016/j.jcmgh.2016.01.006PubMed 27458604

  14. 14

    Laroui H, et al. (2010). Gastroenterology

    DOI: 10.1053/j.gastro.2009.11.003PubMed 19909746

  15. 15

    Dalmasso G, et al. (2008). Gastroenterology

    DOI: 10.1053/j.gastro.2007.10.026

  16. 16

    Kannengiesser K, et al. (2008). Inflamm Bowel Dis

    DOI: 10.1002/ibd.20334PubMed 18092346

  17. 17

    Catania A, et al. (2005). J Pept Res

    DOI: 10.1111/j.1399-3011.2005.00265.xPubMed 15946192

  18. 18

    Elliott RJ, et al. (2004). J Invest Dermatol

    DOI: 10.1111/j.0022-202X.2004.22404.xPubMed 15102092

  19. 19

    Getting SJ, et al. (2003). J Pharmacol Exp Ther

    DOI: 10.1124/jpet.103.051623PubMed 12750433

  20. 20

    Cutuli M, et al. (2000). J Leukoc Biol

    DOI: 10.1002/jlb.67.2.233PubMed 10670585

  21. 21

    Shao W, et al. (2022). Biomater Sci

    DOI: 10.1039/d1bm01466hPubMed 34846053

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About KPV

What is KPV?

KPV is a tripeptide fragment investigated in preclinical cellular research.

What are the molecular formula, molecular weight and CAS number of KPV?

KPV: molecular formula C16H30N4O4, molecular weight 342.43 g/mol and CAS number 67727-97-3.

What is the sequence of KPV?

Lys-Pro-Val (KPV).

How is KPV powder stored?

-20°C; protect from light and moisture; ~24 months.