KPV
A tripeptide fragment investigated in preclinical cellular research.
View KPV in the storeMolecular Profile
- Type
- Synthetic peptide (tripeptide)
- Molecular formula
- C16H30N4O4
- Molecular weight
- 342.43 g/mol
- CAS number
- 67727-97-3
- Amino acids
- 3
- Sequence
- Lys-Pro-Val (KPV)
- Modification
- Free termini; C-terminal tripeptide of alpha-MSH (residues 11-13).
Mechanism & Target Class
The C-terminal tripeptide (Lys-Pro-Val) of alpha-MSH. It is studied in cellular research in the context of the PepT1 (SLC15A1) peptide transporter and NF-kB / MAPK signaling.
Storage & Handling
- Lyophilized
- -20°C; protect from light and moisture; ~24 months.
- Handling
- Small soluble tripeptide; protect from moisture; aliquot.
Primary Database
References (21)
Reviews
1Gravina AG, et al. (2023). Cells
- 2
Brzoska T, et al. (2010). Adv Exp Med Biol
- 3
Brzoska T, et al. (2008). Endocr Rev
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Luger TA, Brzoska T. (2007). Ann Rheum Dis
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Luger TA, et al. (2003). Ann N Y Acad Sci
- 6
Dinparastisaleh R, Mirsaeidi M. (2021). Pharmaceuticals (Basel)
- 7
Adnan SB, et al. (2025). Int J Med Sci
Primary research
8Sung J, et al. (2025). Tissue Cell
- 9
Preclinical delivery study (2024). Front Pharmacol
- 10
Preclinical hydrogel study (2021). PubMed
- 11
Pawar K, et al. (2017). J Pharm Sci
- 12
Xiao B, et al. (2017). Mol Ther
- 13
Viennois E, et al. (2016). Cell Mol Gastroenterol Hepatol
- 14
Laroui H, et al. (2010). Gastroenterology
- 15
Dalmasso G, et al. (2008). Gastroenterology
- 16
Kannengiesser K, et al. (2008). Inflamm Bowel Dis
- 17
Catania A, et al. (2005). J Pept Res
- 18
Elliott RJ, et al. (2004). J Invest Dermatol
- 19
Getting SJ, et al. (2003). J Pharmacol Exp Ther
- 20
Cutuli M, et al. (2000). J Leukoc Biol
- 21
Shao W, et al. (2022). Biomater Sci
