GHK-Cu vs AHK-Cu
GHK-Cu and AHK-Cu are both copper(II) complexes of a three-residue peptide ending in His-Lys: GHK-Cu starts with glycine and AHK-Cu with alanine.
That first residue is the whole sequence difference, and it adds one methyl side chain to the peptide.
Structure side by side
| Property | GHK-Cu | AHK-Cu |
|---|---|---|
| Type | Tripeptide copper(II) complex | Synthetic copper(II)–tripeptide coordination complex |
| Residues | 3 | 3 |
| Sequence | Gly-His-Lys + Cu(II) | Ala-His-Lys + Cu(II) |
| Molecular weight | ~403.9 g/mol (free GHK ligand 340.4 g/mol) | ~416.9 g/mol (AHK-Cu complex); free AHK tripeptide 354.40 g/mol |
| Molecular formula | C14H24CuN6O4 | C15H26N6O4 |
| CAS number | 89030-95-5 | 682809-81-0 |
| Modification | Copper(II) complex of Gly-His-Lys; Cu coordinated by the N-terminal amine, backbone amide nitrogen and histidine imidazole. | Copper(II) chelation via histidine imidazole and backbone nitrogen donor atoms; commonly supplied as the monohydrochloride salt. |
| Form we sell | Lyophilized powder | Not sold here |
| Storage, sealed powder | -20°C, sealed and protected from light/moisture; stable months to years. | Store sealed, protected from light and humidity, at freezer temperature for long-term stability in research settings. |
| References | 31 cited in the record | 20 cited in the record |
Records and products
Questions
What is the structural difference between GHK-Cu and AHK-Cu?
GHK-Cu and AHK-Cu are both copper(II) complexes of a three-residue peptide ending in His-Lys: GHK-Cu starts with glycine and AHK-Cu with alanine. That first residue is the whole sequence difference, and it adds one methyl side chain to the peptide.
How are GHK-Cu and AHK-Cu stored as sealed powder?
GHK-Cu: -20°C, sealed and protected from light/moisture; stable months to years. AHK-Cu: Store sealed, protected from light and humidity, at freezer temperature for long-term stability in research settings.
How is the identity of GHK-Cu and AHK-Cu confirmed?
By mass spectrometry: the measured mass is compared with the expected molecular weight, ~403.9 g/mol for GHK-Cu and ~416.9 g/mol for AHK-Cu. Purity is measured separately by HPLC, and every lot we sell has its certificate at luvaminos.com/coa.
Other comparisons