GHK-Cu

A copper-binding tripeptide investigated in dermal and cellular research.

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Molecular Profile

Type
Tripeptide copper(II) complex
Molecular formula
C14H24CuN6O4
Molecular weight
~403.9 g/mol (free GHK ligand 340.4 g/mol)
CAS number
89030-95-5
Amino acids
3
Sequence
Gly-His-Lys + Cu(II)
Modification
Copper(II) complex of Gly-His-Lys; Cu coordinated by the N-terminal amine, backbone amide nitrogen and histidine imidazole.

Mechanism & Target Class

The copper(II) coordination complex of the tripeptide glycyl-L-histidyl-L-lysine, functioning structurally as a high-affinity copper carrier. Research characterizes its interactions with extracellular-matrix and copper-dependent pathways.

Storage & Handling

Lyophilized
-20°C, sealed and protected from light/moisture; stable months to years.
Handling
A blue/violet color indicates intact copper coordination; avoid freeze-thaw; aqueous stability is pH-dependent.

Primary Database

PubChem CID 378611 ↗

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