Luvaminos

LUV-31 vs MOTS-c

LUV-31 is a 4-residue peptide that starts with a D-arginine, carries a 2',6'-dimethyltyrosine and ends in an amide, while MOTS-c is a 16-residue peptide with no terminal modification recorded.

At ~2,175 g/mol, MOTS-c is more than three times the molecular weight of LUV-31 (unstated).

Structure side by side

LUV-31 and MOTS-c, compared from their research records
PropertyLUV-31MOTS-c
TypeSynthetic aromatic-cationic tetrapeptide (C-terminally amidated, mitochondria-targeted)Mitochondrial-derived peptide (16 residues)
Residues416
SequenceNot stated in the recordMRWQEMGYIFYPRKLR
Molecular weightNot stated in the record~2,175 g/mol
Molecular formulaNot stated in the recordC101H152N28O22S2
CAS numberNot stated in the record1627580-64-6
ModificationNot stated in the recordUnmodified (free base); synthetic preparations are typically supplied as trifluoroacetate or acetate salt. Encoded within the mitochondrial 12S rRNA (MT-RNR1 locus).
Form we sellLyophilized powderLyophilized powder
Storage, sealed powder2–8 °C routine handling; −20 °C or below long-term; protect from light. Lyophilized material reported stable up to 24 months at recommended conditions.-20°C; powder typically stable ~24 months.
References0 cited in the record38 cited in the record

Records and products

Questions

What is the structural difference between LUV-31 and MOTS-c?

LUV-31 is a 4-residue peptide that starts with a D-arginine, carries a 2',6'-dimethyltyrosine and ends in an amide, while MOTS-c is a 16-residue peptide with no terminal modification recorded. At ~2,175 g/mol, MOTS-c is more than three times the molecular weight of LUV-31 (unstated).

How are LUV-31 and MOTS-c stored as sealed powder?

LUV-31: 2–8 °C routine handling; −20 °C or below long-term; protect from light. Lyophilized material reported stable up to 24 months at recommended conditions. MOTS-c: -20°C; powder typically stable ~24 months.

How is the identity of LUV-31 and MOTS-c confirmed?

By mass spectrometry: the measured mass is compared with the expected molecular weight, unstated for LUV-31 and ~2,175 g/mol for MOTS-c. Purity is measured separately by HPLC, and every lot we sell has its certificate at luvaminos.com/coa.

Other comparisons